Calibration procedure

Basic pressure gauge calibration is the comparison of measurement values of a unit under test (your gauge) with those of a more accurate calibrated reference instrument. The purpose of calibration is to maintain the quality and accuracy of measurement and to ensure the proper working of a particular instrument.

It is recommended that any adjustments to a pressure gauge be made only by experienced personnel or the manufacturer. 1.2 This calibration procedure is limited to pressure gauges as classified in Federal Specification GG-G-76E. 3.1 A master gauge is calibrated using a primary pressure standard (see subpar.

1. Check for functionality and any visual defect before calibration.
2. Record all the details about the UUC.
3. Open both ports and exposed to ambient.
4. Connect the pneumatic hose on the positive or high side.
5. Then generate the required pressure (5 test points or as per requirement).

three to six months

If there is a significant difference in the readings (4 or more psi) between the two gauges one or both gauges may be inaccurate. If both gauges read within 1 to 2 psi of each other the gauges are more than likely accurate.

A calibration professional performs calibration by using a calibrated reference standard of known uncertainty (by virtue of the calibration traceability pyramid) to compare with a device under test. He or she records the readings from the device under test and compares them to the readings from the reference source.

Different Types of Calibration

• Pressure Calibration. Pressure calibration is a key function across multiple industries where measurement equipment is used to monitor process performance and safety, typically measuring gas and hydraulic pressure.
• Temperature Calibration.
• Flow Calibration.
• Pipette Calibration.
• Electrical calibration.
• Mechanical calibration.

A calibration indicates the error of the instrument and compensates for any lack of trueness by applying a correction. A verification indicates that the measurement error is smaller than a so called maximum permissible error.

Verification means “proving the truth” or “confirmation”. Verification is an auditing process in which auditor satisfy himself with the actual existence of assets and liabilities appearing in the Statement of Financial position. Thus, verification includes verifying: The existence of the assets and liabilities.

Verification may be accomplished by any combination of the following methods:

• Demonstration. Demonstration is the performance of operations at the system or system element level where visual observations are the primary means of verification.
• Examination.
• Analysis.
• Test.

Calibration verification means the assaying of materials of known concentration in the same manner as patient samples to substantiate the instrument or test system’s calibration throughout the reportable range for patient test results.

D. Criteria for the acceptance of an instrument calibration must be established, such as correlation coefficient or relative standard deviation. The criteria used must be appropriate to the calibration technique employed and must be documented in the laboratory’s standard operating procedure.

Calibration is the foundation of all clinical laboratory testing that insures the accurate reporting of patient results. Calibration is the process that links the analytical signal with the concentration of analyte present in serum, urine or other body fluid. This is the analytical measurement range (AMR).

Verification is a process of “confirming” that a given specification is fulfilled. It is a simple check to confirm that a certain instrument or equipment meets the intended output basing it to the requirements of certain specifications, not a comparison to a higher standard.

Verification means Are we building the product right? Validation is the process of checking whether the software product is up to the mark or in other words product has high level requirements….Related Articles.

“An activity that ensures that an end product stakeholder’s true needs and expectations are met.” Whereas verification takes place while the product is still under development, validation is performed upon the completion of a given module, or even the completion of the entire application.

The meaning of IQ, OQ and PQ are installation qualification, operational qualification and performance qualification, respectively. They represent quality assurance protocols for each phase of the manufacturing process for pharmaceutical equipment.

OQ is Operational Qualification and PQ is Performance Qualification. Before you even get to IQ, OQ, PQ, if you’re acquiring a new piece of equipment, you’ll need design specifications that define exactly what’s in that piece of equipment.

Qualification is a process of assurance that specific system(s), premises or equipment are able to achieve predetermined acceptance criteria to confirm the attributes what it purports to do.

The Process Performance Qualification (PPQ) protocol is a fundamental component of process validation and qualification. Its purpose is to ensure ongoing product quality by documenting performance over a period of time for certain processes.

The Operational Qualification Protocol is a collection of test cases used to verify the proper functioning of a system. The operational qualification test requirements are defined in the Functional Requirements Specification. Operational Qualification is usually performed before the system is released for use.

Design Qualification provides documented verification that the design of new equipment will result in a system that is suitable for the intended purpose. Design Qualification provides documented QA approved evidence: 1. Procured system or equipment meets User Requirements Specification, 2.

Design qualification is defined as a verification process on the design to meet particular requirements relating to the quality of pharmaceuticals and manufacturing practices.

GLOSSARY: Qualification Qualification is defined as an action of providing that equipment or ancillary systems are properly installed, work correctly, and actually lead to the expected results. Qualification is part of validation, but the individual qualification steps alone do not constitute process validation.