The modulation of gene expression can be achieved by a variety of biotechnologies such as RNA interference, non-precision drugs, and artificial transcription factors (ATFs). Epigenome editing is an emerging field of synthetic biology that falls under the category of ATF [1].

Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but they can change how your body reads a DNA sequence. Gene expression refers to how often or when proteins are created from the instructions within your genes.

Summary: We are more than the sum of our genes. Now researchers show robust evidence that not only the inherited DNA itself but also the inherited epigenetic instructions contribute in regulating gene expression in the offspring.

The letters of DNA that we are born with don’t change much over our lifetime. There is an occasional change but it is pretty rare. Methylation is thought to be a different matter though. Scientists think that methylation can change a lot in the DNA of any cell.

Gamma radiation destroys your DNA, but you don’t die from it immediately. Your body still works but your immune system slowly collapses. The same thing would happen to you if all of your DNA disappeared. To keep you alive, your body’s cells constantly replicate themselves by dividing.

If our cells never die and never reproduce, we would remain the same forever. We would not have any children, as the cells don’t reproduce. We wouldn’t age. We could live without air and without food, as our cells never die.

Because DNA is the repository of genetic information in each living cell, its integrity and stability are essential to life. DNA, however, is not inert; rather, it is a chemical entity subject to assault from the environment, and any resulting damage, if not repaired, will lead to mutation and possibly disease.

Our results showed that 30-day intermittent fasting was associated with an anticancer serum proteomic signature, upregulated key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system, and cognitive function, and resulted in a serum proteome protective …

They found that fasting for 3 days or longer–drinking only water and eating less than 200 calories per day–can truly “reset” some components of your immune system.

Fasting means you don’t eat or drink anything but water usually for 8 to 12 hours beforehand. So, if your appointment is at 8 a.m. and you’re told to fast for 8 hours, only water is okay after midnight. If it’s a 12-hour fast, avoid food and drink after 8 p.m. the night before.