To carry out a disintegration test for tablets, we use a basket which holds 1 to 6 tablets. This is then raised and lowered into a beaker of water, which is used to simulate conditions in the stomach at 37°C.

Disintegration Tester is a solid state instrument designed for the accurate estimation of disintegration time of tablets as per IP/USP standards. The instrument is designed to test two batches of six tablets, simultaneously. The unit is extremely useful for pharmaceutical industries.

Disintegration testers are used to test how a drug in pellet form will disintegrate in solution. Like dissolution testers, they permit researchers and medical practitioners to analyze the in vitro breakdown of powdered compounds for quality control purposes.

Why do we do it? Like dissolution testing, Disintegration is often a pharmacopoeial testing requirement for the vast majority of solid dosage forms. It provides critical safety data on drug bioavailability in the body without having to utilise in vivo methods.

Disintegration time is the time required for a dosage form to break up in to granules of specified size (or smaller) under carefully specified conditions. In other words DT (disintegration time) is measuring the break down of a dosage form and dissolution is measuring the drug being solubilized in the media.

11. This test is provided to determine whether tablets or capsules disintegrate within the prescribed time. 12. when placed in a liquid medium under the experimental conditions presented below.

What is Disintegration Testing? Prior to the dissolution of a solid dosage form, it should be established that the tablet or capsule must first disintegrate into smaller parts. Disintegration testing accurately measures, under standard conditions, the ability of a sample to break into smaller particles.

Disintegration is a process of breaking down a substance into tiny fragments to improve its solubility in a solvent. The process is used predominantly in pharmaceutical and chemical industries. Dissolution, on the other hand, is a process through which solutes dissolve in a solvent.

Disintegration is defined as the process of becoming weak or falling apart. An example of disintegration is the process of a sand castle being washed away by water.

The formula for friability test use in tablets: w2= Final weight of tablets or weight after the test.

Manual tablet disintegration tester with two stations. The DT2 is a very easy-to-use and flexible disintegration tester with reliable temperature control. Record and report disintegration times individually per sample or as a completed set.

The Disintegration Testers have a magnetically coupled pump for water circulation in the bath. This 6 station Disintegration Tester comes with 3 pairs of baskets that are controlled by independent timers and motors. Now we will look at the parts that make a Disintegration Tester perform its functions.

This kind of Disintegration Tester automatically detects the individual disintegration times for a tablet or/ and other solid dosage forms. As the word automatic states, they operate independently. They have temperature sensors that enable them to operate within the required temperature limits.

Generally, Disintegration Tester plays an important role in quality control. Besides, it makes research easy and simple. Since the invention of Disintegration Tester, there have been many technological advancements. Besides, there is a high demand for precise and efficient testing apparatus.