The fever usually drops in 10 days, and swollen lymph glands and spleen heal in 4 weeks. Tiredness usually goes away within a few weeks, but it may linger for 2 to 3 months.

Mononucleosis, or mono, is a viral infection that causes fever, sore throat, and swollen lymph glands, most often in the neck.

However, in severe cases of mono it may last as long as six months. Swollen lymph nodes — A person infected with mono may experience swelling of the lymph nodes, primarily in the neck. Swollen tonsils — Following the development of a sore throat, the tonsils become swollen and develop a whitish, yellowish covering.

Infectious mononucleosis–related Epstein–Barr virus (EBV) infection has been associated with an increased risk of Hodgkin’s lymphoma in young adults. Whether the association is causal remains unclear.

These symptoms include:

• extreme fatigue.
• fever.
• sore throat.
• head and body aches.
• swollen lymph nodes in the neck and armpits.
• swollen liver or spleen or both.
• rash.

The virus can cause the body to produce an excessive number of white blood cells called lymphocytes (lymphocytosis). EBV can also weaken the immune system, making it more difficult for the body to fight infection.

Get medical care right away if you have severe belly pain or blurry vision, if you feel lightheaded or confused, or if you pass out. You could have a ruptured spleen. Talk to your doctor if: You have mono symptoms for longer than 10 days or you have a severe sore throat for more than a day or two.

The symptoms of swollen lymph nodes depend upon both the location and cause of the enlargement. Patients may experience symptoms of an upper respiratory infection (runny nose, sore throat, fever) and feel slightly tender or painful nodes under the skin around the ears, under the chin, or on the upper part of the neck under the jaw.

Enlarged lymph node does not always mean cancer; rather it means cancer in rare circumstances. The cancer is caused due to rapidly dividing cells and forms a mass of cells known as tumor. However, the swollen lymph node may be due to the lymph nodes fighting against the infection or due to an autoimmune disease.

Lymph nodes may appear to be painful and swollen as a result of over production of white blood cells (or lymphocytes ). This can be a counter attack for protecting the body against foreign particles. Therefore, a rise in the white blood cell count can cause the lymph nodes to swell and become painful.

Swollen lymph nodes with pain in the neck or throat is often caused by a tonsil infection. When lymph nodes are swollen, they begin taking up space usually occupied by muscles. Swollen lymph nodes may cause neck pain in some people due to pressure.

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