Q. What are MAO inhibitors examples?
MAOIs approved to treat depression
- Isocarboxazid (Marplan)
- Phenelzine (Nardil)
- Selegiline (Emsam)
- Tranylcypromine (Parnate)
Q. What is monoamine oxidase activity?
Monoamine oxidase (MAO) is an enzyme involved in the degradation process for various monoamines released by neurons and glia cells, including DA, serotonin and norepinephrine (NE).
Table of Contents
- Q. What are MAO inhibitors examples?
- Q. What is monoamine oxidase activity?
- Q. What is the function of monoamine oxidase enzyme and where is it located?
- Q. Which are examples of monoamine oxidase inhibitors MAOIs )? Select all that apply?
- Q. Is Escitaloprám an MAOI?
- Q. Is Lamotrigine a monoamine oxidase inhibitor?
- Q. What is the role of monoamine oxidase A?
- Q. Why are Maos important in the breakdown of monoamines?
- Q. Can a monoamine oxidase inhibitor cause hypertension?
- Q. What are enzymes that catalyze the metabolism of monamines?
Q. What is the function of monoamine oxidase enzyme and where is it located?
Monoamine oxidases (MAO) (EC 1.4. 3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body.
Q. Which are examples of monoamine oxidase inhibitors MAOIs )? Select all that apply?
Examples of oral MAOIs include:
- rasagiline (Azilect),
- selegiline (Eldepryl, Zelapar),
- isocarboxazid (Marplan),
- phenelzine (Nardil), and.
- tranylcypromine (Parnate).
Q. Is Escitaloprám an MAOI?
Lexapro is not considered a monoamine oxidase inhibitor (MAOI). MAOIs work by slowing down the breakdown of serotonin and dopamine, another chemical in your brain. This also helps alleviate symptoms of depression.
Q. Is Lamotrigine a monoamine oxidase inhibitor?
Lamotrigine is an anticonvulsant drug effective in the treatment of epilepsy and bipolar depression. Preclinical data showed that lamotrigine inhibited monoamine oxidase (MAO) activity in vitro.
Q. What is the role of monoamine oxidase A?
Monoamine oxidase A (MAOA) is an enzyme involved in the metabolism of the monoamines, eg 5-HT and noradrenaline. It converts the monoamines into their corresponding carboxylic acid via an aldehyde intermediate.
Q. Why are Maos important in the breakdown of monoamines?
MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Q. Can a monoamine oxidase inhibitor cause hypertension?
Monamine oxidase inhibitors can induce severe hypertension when patients consume foods containing tyramine. Some investigators have reported that monoamine oxidase inhibitors cause a severe hypertensive reaction even without use of concomitant medications.
Q. What are enzymes that catalyze the metabolism of monamines?
Monoamine oxidases are enzymes that catalyze the metabolism of monamines including norepinephrine, dopamine, and serotonin among others. Although they metabolize more than catecholamines, they are included in this section.
