Resveratrol has antioxidant and anti-inflammatory properties to protect you against diseases like cancer, diabetes, and Alzheimer’s disease. The anti-inflammatory effects of resveratrol make it a good remedy for arthritis, and skin inflammation.

Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume.

The top food sources include red wine, grapes, some berries and peanuts ( 5 , 6 ). This compound tends to be concentrated mostly in the skins and seeds of grapes and berries. These parts of the grape are included in the fermentation of red wine, hence its particularly high concentration of resveratrol ( 5 , 7 ).

SIRT1 activation: When can I best take resveratrol, pterostilbene, curcumin and quercetin for optimal effect? Key takeaways: ✓ Preferably consumed in the morning, or evening, but not during the day. ✓ Consume with water, with a small meal (breakfast).

After some debate, Harvard Medical School researchers are saying they have confirmed that compound resveratrol that’s found in red wine does provide anti-aging benefits.

Resveratrol might be an effective treatment in the prevention of atherosclerotic changes in arteries and CC. The initial effects of hypercholesterolemia on erectile dysfunction and endothelial dysfunction may be precluded with resveratrol.

Resveratrol appears to have modest therapeutic benefits for improving muscle mass after disuse in aging.

Resveratrol, a plant-based compound found in red grapes and peanuts, exerts beneficial effects on the human brain. Clinical trials have demonstrated that resveratrol reduces levels of amyloid-beta in cerebrospinal fluid and improves cognitive function in people with Alzheimer’s disease.

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage. MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. It seems that HDAC1 is really an anti-aging molecule.

Besides, the phytoestrogen, resveratrolt has received great attention as an upcoming preventive and therapeutic agent against breast cancer. Resveratrol has also shown promise as part of combination therapy, particularly in breast cancer.

Cheng et al. demonstrate that resveratrol exert its anticancer action in in pancreatic cancer cells by suppressing the expression of NAF-1 through activation of Nrf2 signaling and inducing cellular reactive oxygen species accumulation that lead to apoptosis activation and prevent proliferation of pancreatic cancer cells.

trans-resveratrol powder was found to be stable under “accelerated stability” conditions of 75% humidity and 40 °C in the presence of air. The low resveratrol bioavailability was encumbered its therapeutic application.

For example, resveratrol and piceid have similar antioxidant capacity, but piceid appears to be more efficacious than resveratrol due to its reaction with its radical form [22,23]. Indeed, resveratrol-glycoside was more effective than resveratrol against hepatitis B virus [24,25].