Besides the development of a baby, there are many other reasons that cell division is necessary for life:

• To grow and develop, you must form new cells. Imagine how often your cells must divide during a growth spurt.
• Cell division is also necessary to repair damaged cells.
• Your cells can also simply wear out.

Replication is an essential process because, whenever a cell divides, the two new daughter cells must contain the same genetic information, or DNA, as the parent cell. Once the DNA in a cell is replicated, the cell can divide into two cells, each of which has an identical copy of the original DNA.

What are the three reasons that cells typically divide? Get bigger. Repair. Reproduction.

In order to remain healthy, his cells must continue to divide as old cells become worn out or damaged. His body will use both mitosis and meiosis to repair and replace them. Meiosis only produces the sex cells.

In life, muscle cells contract and relax due to the actions of two filamentous proteins (actin and myosin), which slide along each other. After death, the cells are depleted of their energy source and the protein filaments become locked in place.

To illustrate these apoptosis events and how to detect them, Bio-Rad has created a pathway which divides apoptosis into four stages: induction, early phase, mid phase and late phase (Figure 1).

In general, there are three types of cell death, defined in large part by the appearance of the dying cell: apoptosis (also known as type I cell death), autophagic cell death (type II), and necrosis (type III) (Galluzzi et al. 2007).

Morphologically, cell death can be classified into four different forms: apoptosis, autophagy, necrosis, and entosis.

Weight gain was seen at 6 months among users of methotrexate, prednisone, and TNFi. On average, prednisone-treated patients had significantly more weight gain, while leflunomide-treated patients demonstrated weight loss.

Methotrexate was shown to cause a modest amount of weight gain over 6 months, in a study measuring weight changes in people with rheumatoid arthritis. The patients who were most likely to gain weight when starting methotrexate, were patients who had recently lost weight due to rheumatoid arthritis.

Methotrexate sodium is approved to be used alone or with other drugs to treat:

• Acute lymphoblastic leukemia (ALL), including ALL that has spread to the central nervous system, or to prevent it from spreading there.
• Breast cancer.
• Gestational trophoblastic disease.
• Head and neck cancer (certain types).
• Lung cancer.

(1) Methotrexate is an effective steroid-sparing agent.

Methotrexate, sold under the brand name Methoblastin, is an antifolate drug, which means it inhibits the activation of folic acid in the body. It is taken once per week to treat a range of conditions. These include rheumatoid arthritis, the skin disorder psoriasis and inflammatory bowel disease.

Methotrexate is the generic name for the trade drug names Otrexup™, Rasuvo®, Rheumatrex® and Trexall™.