7.8Mechanism of Action Delavirdine binds directly to viral reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme’s catalytic site.

is that pharmacology is (medicine) the science that studies the effects of chemical compounds on living animals, especially the science of the manufacture, use and effects of medicinal drugs while pharmacodynamics is (pharmacology) the branch of pharmacology that studies the effects and modes of action of drugs upon …

Delavirdine is used along with other medications to treat human immunodeficiency virus (HIV) infection. Delavirdine is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood.

Delavirdine (DLV) (brand name Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare.

Saquinavir is an HIV-1 protease inhibitor used in combination with ritonavir and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection.

Tenofovir (TDF) and didanosine (ddI) are among the more often prescribed NRTI for their convenient posology (one pill each per day), relatively high genetic barrier for resistance, quite acceptable safety profile and remarkable antiviral potency when such drugs have been used as single drug or in combinations with …

NNRTIs block reverse transcriptase by binding directly to the enzyme.

Pharmacokinetics is the study of what the body does to the drug, and Pharmacodynamics is the study of what the drug does to the body. But in terms of pharmacodynamics, it refers to how the drug works and how it exerts its power on the body.

Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabo- lism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient.

On the other hand, the word ‘Pharmacodynamics’ is derived from the Greek word ‘ Pharmacon ’ means ‘Drug’ and ‘ Dynamis ’ means ‘Power’. So, pharmacodynamics means drug power. 2. Pharmacokinetics is denoted as PK. While Pharmacodynamics is denoted as PD.

Delavirdine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme’s catalytic site. The activity of Delavirdine does not compete with template or nucleoside triphosphates.

Delavirdine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Delavirdine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme’s catalytic site.

While the example of pharmacodynamics: Loperamide act on μ (Mu)-opioid receptor in the myenteric plexus of the large intestine; decrease smooth muscle tone, and delay the passage of intestinal content. Summary of the difference between Pharmacokinetics and Pharmacodynamics Image of the difference between Pharmacokinetics and Pharmacodynamics