Patients should continue all their anti-thyroid medications and beta blockers until the day of surgery, at which time patients should discontinue taking. Beta blockers may be continued for a few days after surgery and then may be tapered or stopped.

1. Major complications after thyroidectomy, such as bilateral recurrent laryngeal nerve injury with vocal cord adduction or compressive hematoma of the neck require urgent medicosurgical management.

Potential complications include:

• Bleeding.
• Infection.
• Low parathyroid hormone levels (hypoparathyroidism) caused by surgical damage or removal of the parathyroid glands.
• Airway obstruction caused by bleeding.
• Permanent hoarse or weak voice due to nerve damage.

Thereby, the onset of fever, rash, hepatitis, and myositis that were mild and subsided after methimazole withdrawal can be referred to a lupus-like syndrome.

Methimazole prevents the thyroid gland from producing too much thyroid hormone. Methimazole is used to treat hyperthyroidism (overactive thyroid). It is also used before thyroid surgery or radioactive iodine treatment. Methimazole may also be used for purposes not listed in this medication guide.

Long-term use of Tapazole may lead to a remission of hyperthyroidism. Grave’s disease is the most common cause of hyperthyroidism.

The elimination half-life is approximately 5—9 hours. However, the intrathyroidal residence of methimazole is roughly 20 hours, and the duration of action 40 hours, which allows once-daily dosing some patients. The plasma elimination half-life of methimazole is not appreciably altered by the patient’s thyroid status.

People diagnosed with hyperthyroidism usually take the medication methimazole to prevent the thyroid from producing excess hormones. This medication sometimes can initially decrease hormone production too much, and hypothyroidism results.